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US 2011/0237780 A1Published application
Anti-inflammatory dab
AssigneePeptech Limited
InventorsBenjamin P. Woolven, Ian M. Tomlinson, Jennifer A. Lee, Anthony G. Doyle, Philip A. Jennings
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Abstract
The present invention provides a recombinant domain antibody (dAb) which binds to human TNF-α, the dAb comprising an immunoglobulin heavy or light chain variable domain, wherein said variable domain comprises at least one complementarity determining region (CDR) having a sequence derived from a New World primate.
Claims2
A recombinant domain antibody (dAb) which binds TNF-α, wherein the dAb has a sequence consisting of
- (SEQ ID NO:
- 7)
- DIQMTQSPSSLSASVGDRVTITCRASQSIDSYLHWYQQKPGKAPKLLI
- YSASNLETGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQVVWRPF
- TFGQGTKVEIKR.
2 more elements
Dependencies are inferred from the claim text.