Imidazolinylmethyl aryl sulfonamide
AssigneeRoche Palo Alto LLC
InventorsCounde O'Yang, Dennis Mitsugu Yasuda
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Abstract
This invention relates to an alpha-1 A receptor partial agonist, which is represented by Formula I: and pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing formula I, methods for their use as therapeutic agents, and methods of preparation thereof.
Claims11
1-12. (canceled)
The compound N-[3-bromo-2-chloro-4-(4,5-dihydro-1H-imidazol-2-ylmethyl)-phenyl]-methanesulfonamide, or a pharmaceutically acceptable salt, solvate or prodrug thereof.
A method of treating urinary incontinence, the method comprising administering to a subject in need thereof an effective amount of N-[3-bromo-2-chloro-4-(4,5-dihydro-1H-imidazol-2-ylmethyl)-phenyl]-methanesulfonamide, or a pharmaceutically acceptable salt, solvate or prodrug thereof.
A method of treating nasal congestion, the method comprising administering to a subject in need thereof an effective amount of N-[3-bromo-2-chloro-4-(4,5-dihydro-1H-imidazol-2-ylmethyl)-phenyl]-methanesulfonamide, or a pharmaceutically acceptable salt, solvate or prodrug thereof.
Dependencies are inferred from the claim text.