Methods for treating migraines with huperzine a derivatives
OwnerHesheng ZHANGinventor
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Abstract
The present invention relates to a method for treating, alleviating, or preventing pain, particularly migraines, functional pain syndrome, or organic pain syndrome, by administering to a patient in need thereof compound (I), or salts thereof, or pharmaceutical preparations thereof comprising mixtures of compound (I) or salts thereof with pharmaceutically-acceptable diluents wherein: R represents —NR1R2, —NHC(O)OR3, or —N═CR4R5; R1 represents H, or a C1-6 alkyl; R2 represents H, or a C1-6 alkyl; R3 represents a C1-6 alkyl, a heterocyclic group, or an aryl; R4 represents H, C1-6 alkyl, a heterocyclic group or an aryl; and R5 represents H, C1-6 alkyl, a heterocyclic group, or an aryl; or CR4R5 taken together represents a cyclolidene group.
Claims13
A method for treating or alleviating migraines comprising administering to a patient in need thereof a compound of the formula (I), or its salt,
- wherein
- R represents —NR1R2;
- R1 represents H, or a C1-6 alkyl;
- and
- R2 represents H, or a C1-6 alkyl;
A method for treating or alleviating migraines comprising administering to a patient in need thereof a compound of formula (I), or its salt,
- wherein
- R represents —NR1R2;
- R1 represents H, or a C1-6 alkyl;
- R2 represents H, or a C1-6 alkyl;
- and
- except that R1 and R2 are not simultaneously H.
A method for treating or alleviating migraines comprising administering to a patient in need thereof a compound of the formula (I), or its salt,
- wherein
- R represents —NHC(O)OR3, or —N═CR4R5;
- R3 represents a C1-6 alkyl, a heterocyclic group, or an aryl;
- and
- R4 and R5 represent independently a C1-6 alkyl, a heterocyclic group, or an aryl;
- or CR4R5 taken together represents a cyclolidene group.
Dependencies are inferred from the claim text.