Pharmaceutical compositions for the treatment of fungal infections
OwnerFriedrich Karl Mayerinventor
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Abstract
Synergistic combinations of a squalene epoxidase inhibitor and a leucyl-tRNA synthetase inhibitor are provided, which are useful in particular in the treatment of diseases involving fungal or suspected fungal infection, for immunomodulation or immunosuppression in conditions in which fungal or suspected fungal colonisation of e.g. the skin or nail plays a role, such as atopic dermatitis, acne vulgaris, seborrhoeic dermatitis, rosacea or onychomycosis, and in situations of fungal resistance.
Claims7
A pharmaceutical composition comprising a squalene epoxidase inhibitor in combination or association with a leucyl-tRNA synthetase inhibitor, together with at least one pharmaceutically acceptable diluent or carrier.
A kit of parts comprising a squalene epoxidase inhibitor and a leucyl-tRNA synthetase inhibitor in separate unit dosage forms, together with instruction for use.
Dependencies are inferred from the claim text.