Method for treating a mammal by administration of a compound having the ability to release co
AssigneeALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda.
InventorsWerner Haas, Carlos Romao, Beatriz Royo, Ana C. Fernandes, Isabel Goncalves
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Abstract
Several classes of in vivo carbon monoxide-releasing compounds are useful for the treatment and/or prevention of diseases, such as chronic inflammatory, e.g., rheumatoid arthritis, and of diseases with a strong inflammatory component, such as atherosclerosis, stroke, coronary disease, and Alzheimers disease. The in vivo carbon monoxide-releasing compounds can be attached to known drug vectors and/or known anti-inflammatory drugs, such as aspirin.
Claims16
1-43. (canceled)
A pharmaceutical composition for the release of carbon monoxide (CO) in vivo, comprising:
- a CO-containing molybdenum (Mo) complex;
- and
- a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.