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US 2011/0236998 A1Published application
Methods and devices for detection of analytes using bloch surface wave-enhanced diffraction-based sensors
AssigneeThe Governing Council of the University of Toronto
InventorsMarco Liscidini, John Sipe
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Abstract
The invention features methods and diffraction-based devices for the detection of specific analytes. The devices of the invention contain a periodic dielectric multilayer, which allows for the propagation of Bloch surface waves (BSWs) at the surface of the multilayer, thereby increasing the sensitivity of the device.
Claims26
A device for the detection of an analyte in a sample comprising:
- (a) a diffraction grating comprising an immobilized binding agent capable of binding said analyte, and
- (b) a periodic dielectric multilayer, wherein said immobilized binding agent is immobilized on the surface of said periodic dielectric multilayer,
- wherein Bloch surface waves are capable of propagating at the surface of said periodic dielectric multilayer, thereby enhancing diffraction from said diffraction grating.
A diffraction-based device comprising:
- (a) a diffraction grating comprising chemical groups capable of immobilizing a binding agent capable of binding to an analyte, and
- (b) a periodic dielectric multilayer,
- wherein Bloch surface waves are capable of propagating at the surface of said periodic dielectric multilayer, thereby enhancing diffraction from said diffraction grating.
Dependencies are inferred from the claim text.