Emulsions for Microencapsulation Comprising Biodegradable Surface-Active Block Copolymers as Stabilizers
OwnerPeter Marklandinventor
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Abstract
Disclosed herein are surface-active biodegradable block copolymers comprising one or more hydrophobic blocks and one or more hydrophilic blocks. The surface-active polymers are used as stabilizers in emulsions which are used in microencapsulation processes. Also disclosed are microparticles prepared from the emulsions.
Claims20
An emulsion comprising an outer continuous phase of a first liquid and an inner dispersed phase of a second liquid that is at least partially immiscible with the first liquid;
- wherein the emulsion further comprises:
- (a) a biodegradable surface-active block copolymer that comprises one or more hydrophilic blocks and one or more hydrophobic blocks;
- (b) a biodegradable encapsulating polymer;
- and (c) a bioactive agent.
A microparticle comprising a biodegradable polymer matrix comprising a bioactive agent dissolved or dispersed therein and a surface-active block copolymer that comprises one or more hydrophilic blocks and one or more hydrophobic blocks;
- wherein the surface-active block copolymer is dissolved or dispersed in the microparticle or present on the surface of the microparticle.
Dependencies are inferred from the claim text.