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US 2011/0236494 A1Published application
Ciprofloxacin oral suspension
AssigneeRanbaxy Laboratories Limited
InventorsSumit Kumar SAHA, Mona DHALIWAL, Swati AGGRAWAL, Mukesh Kumar GARG, Ajay Kumar SINGLA
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Abstract
The present invention relates to oral taste masked pharmaceutical composition comprising ciprofloxacin or salts or esters thereof. It further relates to processes of preparing it.
Claims19
A taste masked pharmaceutical composition comprising a microgranular core of ciprofloxacin and a taste-masking coating.
A process for making a taste masked pharmaceutical composition, the process comprising:
- (i) dispersing ciprofloxacin and binder in a solvent to form a drug-dispersion;
- (ii) spraying the dispersion of step (i) over inert cores;
- (iii) dispersing water-insoluble and water-soluble coating agents, and optionally a surfactant, in a solvent to form a coating dispersion;
- (iv) coating the cores of step (ii) with the coating dispersion of step (iii) to obtain microgranular cores.
1 more element
Dependencies are inferred from the claim text.