GLUTAMYL tRNA SYNTHETASE (GtS) FRAGMENTS
OwnerYaffa Mizrachi Nebenzahl, Michael Tal +1inventors
InventorsYaffa Mizrachi Nebenzahl, Michael Tal, Ron Dagan
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Abstract
The present invention relates to polypeptide fragments, including variants and analogs, of Streptococcus pneumonia (S. pneumoniae) glutamyl tRNA synthetase (GtS) protein and to vaccines that include such polypeptide fragments. In particular, the present invention relates to the use of such vaccines for eliciting protective immunity to S. pneumoniae.
Claims21
-25. (canceled)
A synthetic or recombinant polypeptide of 50-250 amino acids derived from the sequence of Streptococcus pneumonia (S. pneumoniae) glutamyl tRNA synthetase (GtS) of SEQ ID NO:1, comprising the sequence KNADLETIFEMAKPFLEEAGRLTDKAEKL (SEQ ID NO:2), and variants and analogs thereof.
Dependencies are inferred from the claim text.