Vaccine compositions
OwnerClarisse Marie-Madeleine Lorin, Michele Fevrier +2inventors
InventorsClarisse Marie-Madeleine Lorin, Michele Fevrier, Gerald Hermann Voss, Frederic Tangy
Life of this patent
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Abstract
The present invention relates, inter alia, to a method of raising an immune response against a pathogen which comprises administering (i) one or more first immunogenic polypeptides derived from said pathogen; (ii) one or more viral vectors comprising one or more heterologous polynucleotides encoding one or more second immunogenic polypeptides derived from said pathogen; and (iii) an adjuvant; wherein the one or more first immunogenic polypeptides, the one or more viral vectors and the adjuvant are administered concomitantly. The invention also relates to vaccines, pharmaceutical compositions, kits and uses employing said polypeptides, viral vectors and adjuvants.
Claims27
An immunogenic composition comprising (i) one or more first immunogenic polypeptides from a pathogen;
- (ii) one or more viral vectors comprising one or more heterologous polynucleotides encoding one or more second immunogenic polypeptides from the pathogen;
- and (iii) an adjuvant.
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(canceled)
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A kit comprising (i) one or more first immunogenic polypeptides derived from a pathogen;
- (ii) one or more viral vectors comprising one or more heterologous polynucleotides encoding one or more second immunogenic polypeptides derived from said pathogen;
- and (iii) an adjuvant.
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A method of raising an immune response in a mammal comprising administering to the mammal (i) one or more first immunogenic polypeptides derived from a pathogen;
- (ii) one or more viral vectors comprising one or more heterologous polynucleotides encoding one or more second immunogenic polypeptides derived from said pathogen;
- and (iii) an adjuvant;
- wherein the one or more first immunogenic polypeptides, the one or more viral vectors and the adjuvant are administered concomitantly;
- and optionally repeating the administering one or more times.
Dependencies are inferred from the claim text.