Treatment of biofilms
AssigneeLytix Biopharma AS
InventorsWenche Stensen, Frederick Alan Leeson, Stig Olov Magnus Engqvist, Trond Flægstad, Øystein Rekdal, John Sigurd Svendsen
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Abstract
The present invention relates to a peptide or peptidomimetic for use in the treatment of a biofilm-associated infection in a subject, wherein said peptide or peptidomimetic a) carries a net positive charge, b) is 1 to 6 amino acids in length or is an equivalently sized peptidomimetic; and c) is amphipathic in nature, having one or more lipophilic groups, one of said lipophilic groups comprising at least 7 non-hydrogen atoms.
Claims25
-22. (canceled)
A solid support having covalently attached thereto through a cycloaddition reaction a peptide or peptidomimetic, wherein said peptide or peptidomimetic
- a) carries a net positive charge;
- b) is 1 to 6 amino acids in length or is an equivalently sized peptidomimetic;
- and
- c) is amphipathic in nature, having one or more lipophilic groups, one of said lipophilic groups comprising at least 7 non-hydrogen atoms.
(canceled)
(canceled)
Dependencies are inferred from the claim text.