Multilayer melt-extruded film
OwnerMark J. Hall, Karen A. Coppens +2inventors
InventorsMark J. Hall, Karen A. Coppens, Michael D. Read, Uma Shrestha
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Abstract
High amounts of active ingredients, such as drugs, can be incorporated into a multilayer melt-extruded film which comprises i) one or more active ingredient layers produced from a melt-extruded polymer composition comprising a) a water-soluble polymer and b) an active ingredient; and ii) one or more removable protective layers which leave the active ingredient layer(s) substantially intact upon removal of the protective layer(s).
Claims17
A multilayer melt-extruded film comprising
- i) one or more active ingredient layers produced from a melt-extruded polymer composition comprising a) a water-soluble polymer and b) an active ingredient;
- and
- ii) one or more removable protective layers to leave the active ingredient layer(s) substantially intact.
A multilayer melt-extruded film comprising
- i) one or more active ingredient layers produced from a melt-extruded polymer composition comprising a) a water-soluble polymer and b) an active ingredient;
- and
- ii) one or more protective layers being adjacent to the active ingredient layer(s) and having larger cohesive forces than adhesive forces to the active ingredient layer(s).
A process for producing a melt-extruded film comprising the step of coextruding
- i) one or more active ingredient layers produced from a melt-extruded polymer composition comprising a) a water-soluble polymer and b) an active ingredient;
- ii) one or more removable protective layers to leave the active ingredient layer(s) substantially intact after removal of the protective layer(s);
- and
- iii) optionally an excipient layer between the active ingredient layer(s) and the protective layer(s).
A process for producing a melt-extruded film comprising the step of coextruding
- i) one or more active ingredient layers produced from a melt-extruded polymer composition comprising a) a water-soluble polymer and b) an active ingredient;
- and
- ii) one or more protective layers having larger cohesive forces than adhesive forces to the active ingredient layer(s).
Dependencies are inferred from the claim text.