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US 2011/0236365 A1Published application
Method for protecting and treating at least one muscarinic receptor from dysfunction resulting from free radical damage
AssigneeHealthPartners Research Foundation
InventorsWilliam H. Frey, II, John Randall Fawcett
Life of this patent
Estimating the term…
Abstract
Methods and compositions for enhancing cellular function through protection of a tissue components such receptors, proteins, lipids, nucleic acids, carbohydrates, hormones, vitamins, and cofactors, by administering pyrophosphate analogs or related compounds.
Claims26
1-80. (canceled)
A method for protecting and treating at least one muscarinic receptor from dysfunction resulting from free radical damage in a subject in need thereof, comprising:
- administering an effective amount of bisphosphonate directly to the CNS of the subject and bypassing the blood-brain barrier by intranasally administering to the upper one-third of the subject's nasal cavity the effective amount of bisphosphonate;
- and
- protecting or treating the muscarinic receptors from the dysfunction resulting from free radical damage in the subjects in need thereof.
Dependencies are inferred from the claim text.