Peptide targeting imaging agents and methods of use thereof
AssigneeUniversity of Utah Research Foundation
InventorsZheng-Rong Lu, Furong Ye
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Abstract
Described herein are peptide targeting imaging agents. The peptides are covalently attached to the imaging agent and have a specific peptide sequence that enables the imaging agent to accumulate specifically in tumor tissues. Additionally, the imaging agents are readily excreted by the subject within a short period of time after administration to the subject. Methods for using the imaging agents are also described herein.
Claims23
A compound comprising a cyclic peptide covalently attached to an imaging agent, wherein the cyclic peptide comprises the sequence SEQ ID NO 1 or SEQ ID NO 2, a linear peptide comprising the sequence SEQ ID NO 3, or any degenerate variant thereof.
Dependencies are inferred from the claim text.