Medical fluid access device with antiseptic indicator

An antiseptic indicator, comprising:

• a substrate;
• and
• a microporous layer disposed on the substrate, the microporous layer made from a polymer material having an index of refraction from about 1.25 to about 1.6 and configured to change from a substantially opaque state to a transparent state upon exposure to an antiseptic solution, and wherein the microporous layer resumes the substantially opaque state after a period of time.

A medical device, comprising:

• a medical device having a surface;
• and
• an indicator atop the surface, the indicator comprising an optically active, surface layer that is configured to change from a first appearance to a second appearance upon exposure to an antiseptic solution, and wherein the indicator substantially resumes the first appearance after a period of time.