Retinal imaging system for the mouse or rat or other small animals
AssigneeUniversity of Miami
InventorsOmer Kocaoglu, Stephen Uhlhorn, Eleut Hernandez, Vittorio Porciatti, Jean-Marie Parel, Fabrice Manns
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Abstract
A small animal imaging system comprising a base element and a camera coupled to the base element, the camera being sized to image the eye of a small animal. A light-emitting diode is also included coupled to the base element. An OCT imaging apparatus is also included coupled to the base element. An X-Y scanner is also included coupled to the base element in communication with the OCT imaging apparatus.
Claims20
A small animal imaging system comprising:
- a base element;
- a camera coupled to the base element and sized to image the eye of a small animal;
- a light-emitting diode coupled to the base element;
- an OCT imaging apparatus coupled to the base element;
- and
- an X-Y scanner coupled to the base element in communication with the OCT imaging apparatus.
A method for imaging the eye of a mouse comprising:
- providing an OCT imaging apparatus and a camera sized to image the fundus of a small animal;
- optically aligning the camera with the fundus of a small animal;
- visualizing a desired area of the fundus for OCT imaging;
- illuminating the desired area of the fundus with light from a light-emitting diode;
- acquiring an image of the fundus;
- and
- imaging the desired area of the fundus with the OCT imaging apparatus.
A small animal imaging system comprising:
- a base element;
- a camera coupled to the base element and sized to image the eye of a small animal;
- an OCT imaging apparatus coupled to the base element;
- a light-emitting diode coupled to the base element;
- a first illumination lens coupled to the base element proximate the light-emitting diode;
- a reflection mirror coupled to the base element proximate the first illumination lens, the reflection mirror defining an aperture approximately at its center;
- a second illumination lens coupled to the base element, the second illumination lens being oriented such that a longitudinal axis defined by the second illumination lens is substantially parallel to a longitudinal axis defined by the first illumination lens;
- a first folding mirror coupled to the base element, the first folding mirror being oriented such that a longitudinal axis defined by the first folding mirror is substantially parallel to a longitudinal axis defined by the reflection mirror;
- a second folding mirror coupled to the base element, the second folding mirror being oriented such that a longitudinal axis defined by the second folding mirror is substantially perpendicular to the longitudinal axis defined by the first folding mirror;
- a hot mirror coupled to the base element, wherein the hot mirror allows light emitted by the light-emitting diode to pass through the hot mirror and reflects infrared wavelengths of light generated by the OCT imaging apparatus;
- a scanning lens coupled to the base element, the scanning lens being disposed between the second folding mirror and the hot mirror;
- an auxiliary lens coupled to the base element;
- a collimating lens coupled to the base element proximate the OCT imaging apparatus;
- and an X-Y scanner coupled to the base element in communication with the OCT imaging apparatus.
Dependencies are inferred from the claim text.