Characterization of molecules
AssigneeAnaliza, Inc.
InventorsArnon Chait, Boris Zaslavsky
Life of this patent
Estimating the term…
Abstract
The invention involves obtaining signatures of species (including chemical, biological, or biochemical molecules) and/or signatures of interactions between species and using them to characterize species, characterize interactions, and/or identify species that could be useful in a variety of settings. Signatures can be obtained using aqueous multi-phase partitioning and can be used to predict molecular interactions for applications such as drug discovery. A plurality of aqueous multi-phase partitioning arrangements can define an overall system providing an information-intensive signature, maximizing precision and sensitivity.
Claims11
1-24. (canceled)
A method for predicting the level of biological activity of interest of a biomolecule that is bound to a binding partner, comprising:
- a) obtaining a reference signature of a biomolecule bound to a binding partner for which a reference level of biological activity of interest is known;
- b) determining a relationship between the reference signature of the biomolecule and the reference level of biological activity;
- c) obtaining the signature of the biomolecule bound to an experimental binding partner;
- d) comparing the signature of c) and the relationship derived in b);
- and
- e) predicting the biological activity of the experimental binding partner.
34-40. (canceled)
Dependencies are inferred from the claim text.