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US 2011/0218611 A1Published application
Drug eluting stent and a guide catheter device assembly for implanting the same
OwnerVipul Narain Royinventor
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Abstract
The present invention relates to a drug eluting stent for delivering therapeutic agents to a body lumen. The stent includes an expandable substrate configured for implantation in a vessel of a human body and a therapeutic agent composition coated over the stent. The balloon catheter shaft has a resilient unit that helps to transmit a force to the distal end, thereby helping to cross lesions.
Claims21
A drug eluting stent for delivering therapeutic agents to a body lumen, the stent comprising:
- a stent comprising a expandable substrate configured to be implanted in a vessel of a human body;
- and
- a therapeutic agent composition coated over the stent, the therapeutic agent composition comprising
- anticoagulants,
- Platelet Glycoprotein IIb/IIIa Receptor blocker or antagonist, and
- a cytostasis or cytotoxic agent,
- wherein,
- the proportion of the anticoagulants, the Platelet Glycoprotein IIb/IIIa Receptor blocker or antagonist, and the cytostasis or cytotoxic agent having a range of 1:0.15:0.5 to 1:0.2:1, and
- edges of the stent have a 3-30 times higher concentration of drugs as compared to middle segment of the stent to obtain a desired release profile of the coated composition.
6 more elements
A guide catheter device for angioplasty, comprising:
- a guide catheter having a proximal end, a distal end, and lumen extending therethrough;
- a balloon catheter placed inside the guide catheter, the balloon catheter having a proximal end, a distal end, a guide wire lumen and a balloon lumen;
- a fluid inflatable balloon connected to the distal end of the balloon lumen;
- a guide wire extending through the guide wire lumen of the balloon catheter;
- and
- a drug eluting stent mounted over the balloon in order to place the same at a desired location in the artery;
- wherein,
- at least one resilient unit is provided at a predetermined distance from the proximal end of the balloon catheter that is configured to absorb and transmit a required force to maintain the alignment of the guide catheter and the balloon catheter;
- and
- edges of the stent have a higher concentration of drugs as compared to a middle segment of the stent.
7 more elements
Dependencies are inferred from the claim text.