Novel compound with spiro chiral carbon backbone, preparation method thereof, and pharmaceutical composition containing the same

A compound of Formula 1 below, a stereoisomer thereof, an enantiomer thereof, an in vivo-hydrolysable precursor thereof, or a pharmaceutically acceptable salt thereof:

• wherein:
• W is CO or CHOR1;
• X is N3, NHR2, OR2, SR2, SeR2 or TeR2;
• R1 and R2 are, independently, selected from hydrogen, straight or branched C3˜C8 alkyl, C2˜C8 alkenyl, C2˜C8 alkynyl, C3˜C8 cycloalkyl, C6˜C20 aryl, C4˜C20 heteroaryl or
• Y is O, S or NR4;
• Z is a single bond, NH, O, S, Se or Te;
• R3 and R4 each are independently selected from hydrogen, straight or branched C1˜C8 alkyl, C2˜C8 alkenyl, C2˜C8 alkynyl, C3˜C8 cycloalkyl, C6˜C20 aryl, or C4˜C20 heteroaryl;
• and
• M and N each are independently hydrogen, OH, or do not exist;
• wherein a carbon atom bonded to M or N forms a single bond or a double bond with other carbon atoms and the number of double bonds is one or less for each of the carbon atoms.