Hydrate crystals
AssigneeAjinomoto Co., Inc.
InventorsKenichi MORI, Eriko ONO
Life of this patent
Estimating the term…
Abstract
New (2R,4R) monatin monosodium salt hydrate crystals characterized by having specific characteristic X-ray diffraction peaks provide general-purpose, stable, and safe monatin sodium salt crystals incorporating no organic solvent. These crystal may be prepared by a method that requires no organic solvent in the crystallization, separation, and drying steps. These crystal are useful as sweeteners and for the preparation of orally consumed products, such as foods, beverages, pharmaceutical products, topical pharmaceutical products, and feeds containing general-purpose, stable, and safe monatin sodium salt crystals.
Claims17
(2R,4R) Monatin monosodium salt hydrate crystals, having characteristic X-ray diffraction peaks at angles of diffraction (2θ±0.2°, CuKα) of either:
- group (A) 7.7°, 10.9°, 16.7°, and 17.0°;
- or
- group (B) 4.7°, 12.4°, 18.8°, and 22.6°.
Monatin crystals, having characteristic X-ray diffraction peaks at angles of diffraction (2θ±0.2°, CuKα) of either:
- group (A) 7.7°, 10.9°, 16.7°, and 17.0° or
- group (B) 4.7°, 12.4°, 18.8°, and 22.6°.
A method for making (2R,4R) Monatin monosodium salt hydrate crystals, having characteristic X-ray diffraction peaks at angles of diffraction (2θ±0.2°, CuKα) of 7.7°, 10.9°, 16.7°, and 17.0°, said method comprising:
- allowing an aqueous solution containing a high concentration of (2R,4R) monatin monosodium salt to stand or subjecting it to stirring precipitation to obtain said crystals.
A method for making (2R,4R) Monatin monosodium salt hydrate crystals, having characteristic X-ray diffraction peaks at angles of diffraction (2θ±0.2°, CuKα) of 4.7°, 12.4°, 18.8°, and 22.6°, said method comprising:
- concentrating an aqueous solution containing a high concentration of (2R,4R) monatin monosodium salt, to obtain a concentrated solution;
- introducing a water-miscible solvent into said concentrated solution, to obtain a mixture;
- and
- allowing said mixture to stand or inducing crystallization by stirring.
Dependencies are inferred from the claim text.