Topical vasoconstrictor preparations and methods for protecting cells during cancer chemotherapy and radiotherapy
AssigneeWisconsin Alumni Research Foundation
InventorsWilliam E. Fahl, Arnold E. Ruoho, Minesh Mehta
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Abstract
Vasoconstrictors are administered topically to provide protection against the adverse effects, e.g., alopecia, mucositis or dermatitis, induced by chemotherapy or radiotherapy. Appropriate dosages and formulations of topical vasoconstrictors are provided. Methods for the use of such compositions are also provided.
Claims12
-42. (canceled)
A topical vasoconstrictor formulation comprising a vasoconstrictor that is an agonist of the α1 adrenergic receptor, but is not an agonist of the β2 adrenergic receptor, and a pharmaceutically-acceptable delivery vehicle that comprises at least 50% alcohol.
Dependencies are inferred from the claim text.