Composition for down-regulating pro-inflammatory markers
OwnerMuhammed Majeed, Anjali Pandey +2inventors
InventorsMuhammed Majeed, Anjali Pandey, Sarang Bani, Beena Bhat
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Abstract
The present invention provides a composition for down-regulating pro-inflammatory markers. The composition comprises boswellic acid fraction and polysaccharide faction obtained from Boswellia species at specific concentrations showing enhancement in their activity as compared to boswellic acid fraction and the polysaccharide fraction alone. The invention further comprises use of polysaccharide fraction individually or in combination with boswellic acid fraction for inhibition of PGE2.
Claims17
1) A synergistic composition comprising boswellic acid fraction at a concentration of about 60% and polysaccharide fraction at a concentration of about 40%. optionally along with pharmaceutically acceptable excipients.
7) A process for preparing synergistic composition comprising boswellic acid fraction at a concentration of about 60% and polysaccharide fraction at a concentration of about 40% optionally along with pharmaceutically acceptable excipients, said process comprising steps of:
- obtaining boswellic acid fraction and polysaccharide fraction from Boswellia species;
- combining the boswellic acid fraction at a concentration of about 60% and the polysaccharide fraction at a concentration of about 40% optionally along with pharmaceutically acceptable excipients to obtain the composition.
10) A method for down-regulating/inhibiting pro-inflammatory markers, said method comprising step of administering a composition comprising boswellic acid fraction at a concentration of about 60% and polysaccharide fraction at a concentration of about 40% optionally along with pharmaceutically acceptable excipients to a subject in need thereof.
14) A method for down-regulating/inhibiting PGE2, said method comprising step of administering a composition comprising polysaccharide fraction alone or in combination with boswellic acid fraction optionally along with pharmaceutically acceptable excipients to a subject in need thereof.
Dependencies are inferred from the claim text.