Dna cytosine deaminase inhibitors

A method for inhibiting APOBEC3G activity in a mammal, said method comprising administering to said mammal a therapeutically effective amount of a compound of Formula (I):

• wherein:
• R1, R2, and R4 are independently chosen from H, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, and substituted or unsubstituted alkynyl;
• R3 is chosen from H and ORS;
• and
• R5 is chosen from H and substituted or unsubstituted alkyl;
• or a pharmaceutically acceptable salt form thereof;
• a therapeutically effective amount of a compound of Formula (II):
• wherein:
• R6, R7, and R8 are independently chosen from H and substituted or unsubstituted alkyl;
• and
• R9 is chosen from a substituted or unsubstituted cycloalkyl and substituted or unsubstituted heterocycloalkyl;
• or a pharmaceutically acceptable salt form thereof;
• a therapeutically effective amount of a compound of Formula (III):
• wherein:
• R10 and R11 are independently chosen from H and substituted or unsubstituted alkyl;
• and
• R12 is chosen from:
• (CH2)nC(O)OR22, and substituted or unsubstituted alkylaryl;
• wherein:
• R13 is chosen from C(O)NR14R15, C(O)OR14, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl;
• R14 is chosen from H and substituted or unsubstituted alkyl;
• R15 is a substituted or unsubstituted alkylaryl;
• R16 is chosen from H and substituted or unsubstituted alkyl;
• R17 is chosen from H and C(O)OR20;
• R18 and R19 are chosen from H, C(O)R21, and amino;
• R20 and R21 are independently chosen from H and substituted or unsubstituted alkyl;
• R22 is H or a substituted or unsubstituted alky;
• and
• n is an integer from 1 to 6;
• wherein if R16 is methyl, then at least one of R18 and R19 is not H;
• or a pharmaceutically acceptable salt form thereof;
• or a therapeutically effective amount of a compound of Formula (IV):
• wherein:
• R23 and R24 are independently chosen from H and substituted or unsubstituted alkyl;
• R25 is a substituted or unsubstituted heterocycloalkyl and R26 is H, or R25 and R26 come together to form a substituted or unsubstituted cycloalkyl or a substituted or unsubstituted heterocycloalkyl;
• or a pharmaceutically acceptable salt form thereof.