Topical Glutathione Formulations For Menopausal Skin
AssigneeN.V. Perricone LLC
InventorNicholas V. Perricone
Life of this patent
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Abstract
Topical compositions to address menopausal skin conditions comprise an effective amount of S-acyl glutathione derivative and a carrier. Methods for addressing menopausal skin conditions comprise applying a composition containing S-acyl glutathione derivative in a dermatologically acceptable carrier to skin tissue. The acyl group is a saturated or unsaturated aliphatic C12-C24 group, preferably an unsaturated C16-C24 group, most preferably an unsaturated C18 group. In particularly preferred embodiments, the acyl group is a linoleoyl group.
Claims34
A method of improving the appearance of peri-menopausal, menopausal, or post-menopausal skin comprising:
- applying to the skin tissue of a mammal in need of such regulation, a safe and effective amount of a composition containing S-acyl glutathione derivative of formula (I)
- wherein R1 consists of a saturated or unsaturated aliphatic C12-C24 group and R2 is a hydrogen, aliphatic or aromatic acyl group;
- and a dermatologically acceptable carrier.
A method of preventing or retarding exaggerated lines and wrinkles of peri-menopausal, menopausal, or post-menopausal skin comprising:
- applying to the skin tissue of a mammal in need of such regulation, a safe and effective amount of a composition containing S-acyl glutathione derivative of formula (I)
- wherein R1 consists of a saturated or unsaturated aliphatic C12-C24 group and R2 is a hydrogen, aliphatic or aromatic acyl group;
- and a dermatologically acceptable carrier.
A method of preventing or retarding the appearance of spider vessels or red blotchiness in peri-menopausal, menopausal, or post-menopausal skin comprising:
- applying to the skin tissue of a mammal in need of such regulation, a safe and effective amount of a composition containing S-acyl glutathione derivative of formula (I)
- wherein R1 consists of a saturated or unsaturated aliphatic C12-C24 group and R2 is a hydrogen, aliphatic or aromatic acyl group;
- and a dermatologically acceptable carrier.
A method of improving the appearance of peri-menopausal, menopausal, or post-menopausal skin comprising:
- applying to the skin tissue of a mammal in need of such regulation, a safe and effective amount of a composition containing S-linoleoyl glutathione in a dermatologically acceptable carrier.
A method of improving the appearance of peri-menopausal, menopausal, or post-menopausal skin comprising:
- applying to the skin tissue of a mammal in need of such regulation, a safe and effective amount of a composition containing reduced glutathione in a dermatologically acceptable carrier.
Dependencies are inferred from the claim text.