Activin-actriia antagonists for inhibiting germ cell maturation
AssigneeAcceleron Pharma Inc.
InventorsJohn Knopf, Jasbir Seehra, Matthew L. Sherman
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Abstract
In certain aspects, the present invention provides compositions and methods for decreasing FSH levels in a patient. The patient may, for example, be diagnosed with an FSH-related disorder or desire to delay or inhibit germ cell maturation.
Claims12
A method for inhibiting FSH production in a patient desiring to delay or inhibit his or her germ cell maturation, the method comprising administering an amount of ActRIIa-Fc fusion protein effective to reduce FSH activity in the subject, wherein the ActRIIa-Fc fusion protein comprises an amino acid sequence that is at least 90% identical to the amino acid sequence of SEQ ID NO:
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Dependencies are inferred from the claim text.