Ordered two- and three-dimensional structures of amphiphilic molecules
OwnerFatemeh MOJTABAIinventor
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Abstract
The invention pertains, at least in part, to a method for forming an ordered structure of amphiphilic molecules, such as proteins. The method includes contacting a population of amphiphilic molecules with a interface; compressing said population laterally to an appropriate pressure, such that an ordered structure at the interface is formed. The invention also pertains to the two- and three-dimensional ordered structures that are formed using the planar membrane compression method of the invention.
Claims33
-28. (canceled)
A method for determining the shape of an amphiphilic molecule, comprising
- contacting a population of said molecule with a interface;
- compressing said population to an appropriate pressure, such that an ordered structure is formed at said interface, and
- analyzing said ordered structure such that the shape of said amphiphilic molecule is determined.
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A method for screening a test compound, comprising:
- contacting said test compound with an ordered structure;
- and
- analyzing the results of the interaction of said test compound and the ordered structure, such that said test compound is screened.
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A protein chip, comprising a solid support and at least one ordered structure of an amphiphilic molecules.
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-58. (canceled)
A method for determining the structure of a protein, comprising:
- expressing said protein in a cell;
- obtaining said protein from said cell;
- applying said protein to an interface;
- compressing said protein on said interface to an appropriate pressure, such that an ordered structure of said protein is formed;
- and
- analyzing said ordered structure such that the structure of said protein is determined.
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Dependencies are inferred from the claim text.