Cleavable surfactants and methods of use thereof

A cleavable surfactant/detergent compound of the following formula:

• (A) wherein the polar head is chosen from:
• cystine,
• cystine containing peptides with 6 amino acids or less,
• furanose,
• pyranose,
• polysaccharides with 3 carbohydrates or less, and
• polyethylene glycol, wherein n is 1-12 above;
• and
• (B) the cleavable linker is chosen from:
• where R1 is independently —H or —(CH2)0-19CH3,
• R2 is independently —CH3,
• where X is —NH2 or OH,
• R3 is —H, —CH3, —F, —Cl, —Br, —I, or, —CN.