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US 2011/0217377 A1Published application
Long Circulating Nanoparticles for Sustained Release of Therapeutic Agents
OwnerStephen E. Zale, Greg Troiano +4inventors
InventorsStephen E. Zale, Greg Troiano, Mir M. Ali, Jeff Hrkach, James Wright, Susan Low
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Abstract
The present disclosure is directed in part to a biocompatible nanoparticle composition comprising a plurality of non-colloidal long circulating nanoparticles, each comprising a α-hydroxy polyester-co-polyether and a therapeutic agent, wherein such disclosed compositions provide a therapeutic effect for at least 12 hours.
Claims14
A nanoparticle comprising a polymer matrix and a therapeutic agent coupled to the polymer matrix wherein the polymer matrix is biodegradable and/or biocompatible.
Dependencies are inferred from the claim text.