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US 2011/0217357 A1Published application
Method for solubilizing metronidazole
AssigneeGalderma S.A.
InventorsClaire MALLARD, Alain Brzokewicz
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Abstract
Metronidazole is solubilized in an aqueous phase, by mixing same with niacinamide and at least two glycolic cosolvents; the resulting solutions and pharmaceutical compositions comprised thereof are useful for the treatment of dermatological conditions/afflictions, notably rosacea.
Claims21
A process for solubilizing metronidazole, comprising intimately admixing, in an aqueous phase, said metronidazole with niacinamide or salt thereof and at least two glycolic cosolvents, in the absence of cyclodextrin.
An aqueous solution comprising metronidazole, niacinamide or salt thereof and at least two glycolic cosolvents.
Dependencies are inferred from the claim text.