US 2011/0217339 A1Published application

Mucoactive agents for treating a pulmonary disease

AssigneeVectura Limited

InventorsDavid MORTON, David GANDERTON, John STANIFORTH, Yorick KAMLAG

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Abstract

The present invention relates to pharmaceutical compositions which are useful in the treatment of diseases where excess mucus is present in the respiratory tract, such as cystic fibrosis and chronic obstructive pulmonary disease. In particular, the invention relates to pharmaceutical compositions for administration by pulmonary inhalation.

Claims46

Dependent claims

A composition for assisting mucus clearance, the composition comprising one or more mucoactive agents which assist mucous clearance through one or more of the following mechanisms:

reducing cross-linking within the mucus, diluting the mucus, and digesting naked DNA and cell debris within the mucus.

Dependencies are inferred from the claim text.

Facts

Application: 13/043,117Filed 8 Mar 2011
Priority: GB 0321611.615 Sep 2003
Published: 8 Sep 2011
Term ends: Not estimatedThe source records don’t support an estimate.

Classification11 codes

A61K 31/198
The amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine,…:…
A61K 9/0073
Pulmonary tract; Aromatherapy: sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
A61K 31/727
Glycosaminoglycans, i.e. mucopolysaccharides: heparin; Heparan
A61P 11/00
Drugs for disorders of the respiratory system

Family

Application10/571,184Continuation · filed 17 Jul 2006
Application13/043,117Continuation
US 2007/0065373 A1Published application
US 7,928,089 B2Related patent
US 2011/0217339 A1This patent

From the US filing history. Foreign family members aren’t listed.

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