Hypoallergenic molecules
AssigneeBiomay AG
InventorsMichael Wallner, Barbara Bohle, Martin Himly, Nicole Wopfner, Gabriele Gadermaier, Matthias Egger, Peter Lackner, Fatima Ferreira, Michael Hauser
Life of this patent
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Abstract
The present invention relates to a hypoallergenic molecule consisting of Bet v Ia or an allergen having at least 40% identity to Bet v Ia comprising mutations of at least four amino acid residues in the region of amino acids 100 to 125 of Bet v Ia or its corresponding region of the allergen having at least 40% identity to Bet v Ia.
Claims17
Hypoallergenic molecule consisting of Bet v 1a or an allergen having at least 40% identity to Bet v 1a comprising mutations of at least one amino acid residue in the region of amino acids 100 to 125 of Bet v 1a or its corresponding region of the allergen having at least 40% identity to Bet v 1a, wherein the mutation of at least one amino acid residue comprises the mutation of amino acid residue at position 114 of Bet v 1a or the allergen having at least 40% identity to Bet vIa.
A hypoallergenic molecule consisting of Bet v 1a or an allergen having at least 40% identity to Bet v 1a comprising mutations of at least four amino acid residues in the region of amino acids 100 to 125 of Bet v 1a or its corresponding region of the allergen having at least 40% identity to Bet vIa.
A use of hypoallergenic molecule according to claim for the manufacture of a vaccine for the prevention and/or treatment of allergies.
Dependencies are inferred from the claim text.