Back to results
US 2011/0217291 A1Published application
Soluble hybrid fct receptors and related methods
AssigneeZymoGenetics, Inc.
InventorsCarl W. Birks, Brian A. Fox, Mark W. Rixon, Jeff L. Ellsworth
Life of this patent
Estimating the term…
Abstract
Disclosed are soluble hybrid Fcγ receptor (FcγR) polypeptide compositions and related methods of using such polypeptides to treat IgG-mediated and immune complex-mediated inflammation. Also disclosed are related compositions and methods for producing the soluble hybrid FcγR polypeptides.
Claims27
An isolated, soluble polypeptide comprising an amino acid sequence having at least 90% sequence identity with a polypeptide region selected from the group consisting of
- amino acid residues 36-301 of SEQ ID NO:40;
- amino acid residues 43-310 of SEQ ID NO:42;
- amino acid residues 21-286 of SEQ ID NO:44;
- or
- amino acid residues 21-286 of SEQ ID NO:46;
- wherein said polypeptide is capable of specifically binding the Fc region of IgG.
3 more elements
Dependencies are inferred from the claim text.