Treatment and/or prevention of peanut induced anaphylaxis
OwnerManel Jordana, Susan Waserman +1inventors
InventorsManel Jordana, Susan Waserman, Katherine Arias
Life of this patent
Estimating the term…
Abstract
Compositions and methods for the treatment of food allergies, particularly peanut allergy are provided. The compositions and methods are based on the observation that agents which interfere with the association of platelet activating fact (PAF) with its receptor (PAF-R) significantly reduce the severity and duration of anaphylaxis. Combination therapy with a PAF inhibitor and a histamine inhibitor provided an increased beneficial effect compared to treatment alone.
Claims16
A pharmaceutical composition for the prevention or treatment of a food allergy comprising an agent that reduces PAF activity.
A method of preventing or treating anaphylaxis comprising administering an agent that alters PAF activity in a manner and amount to reduce PAF activity.
Dependencies are inferred from the claim text.