Keratin biomaterials for treatment of ischemia
AssigneeWake Forest University Health Sciences
InventorsMark E. Van Dyke, Thomas L. Smith, Michael Callahan, Luke Burnett
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Abstract
Provided herein are keratin compositions useful for treating ischemia and/or reperfusion injury, such as that associated with myocardial infarct, ischemic stroke, brain trauma such as traumatic brain injury, hypothermia, chronic wounds, and burns.
Claims26
A method of treating ischemia or reperfusion injury in a subject in need thereof, said method comprising administering a composition comprising a keratin to said subject in an amount effective to treat said ischemia or reperfusion injury.
The method of claim 4, wherein said α-keratose has an average molecular weight of at least 30 kiloDaltons.
A composition comprising a keratin and further comprising a thrombolytic.
A composition comprising a keratin and further comprising an anticoagulant.
Dependencies are inferred from the claim text.