Kidney cell carcinoma

A process for the diagnosis of a renal cell carcinoma, comprising the steps of:

• a) separating a sample into at least three, preferably at least 10, subsamples;
• b) analyzing at least three, preferably at least 10, subsamples by measuring the presence or absence or amplitude of at least one polypeptide marker in the sample, wherein said polypeptide marker is selected from the markers of Table 1, which are characterized by the molecular masses and migration times (CE time), and the CE time relates to a glass capillary of 90 cm in length and with an inner diameter (ID) of 50 μm at an applied voltage of 25 kV, and 20% acetonitrile, 0.25% formic acid in water is used as the mobile solvent.

A device for the quantitative evaluation of the polypeptide markers found in a urine sample, wherein said device comprises a data base containing data sets corresponding to reference values of polypeptides, and information about the presence or absence or amplitude of the polypeptides in samples from healthy or ill subjects, wherein said data base at least contains information relating to the identity of the markers and the presence and absence or amplitude of three polypeptide markers from Table 1.