Electromagnetic signal delivery for tissue affected by neuronal dysfunction, degradation, damage, and/or necrosis, and associated systems and methods

A method for treating a patient after an ischemic stroke using electrical stimulation, comprising:

• identifying a location of an infarct region having dysfunctional neuronal tissue that was subjected to a reduced oxygen supply;
• based at least in part on the location of the infarct region, identifying an affected region located in a deep brain region of the patient's brain having low morbidity tissue;
• selecting a first set of stimulation parameters such that the neuronal tissue in the affected region is stimulated during a post-acute, pre-chronic period relative to onset of damage to the low morbidity tissue in the affected region;
• and
• selecting a second set of stimulation parameters such that the neuronal tissue in the affected region is stimulated during a chronic period once the onset of damage to the low morbidity tissue has occurred;
• and
• controlling a pulse generator to generate electrical pulses and to apply the electrical pulses to the patient through an electrode according to the first and second set of stimulation parameters.