Method and device for devitalizing biological tissue

A device for devitalizing biological tissue, said device comprising:

• at least one ablation probe having cooling devices configured and arranged such that tissue regions close to the at least one ablation probe can be cooled by the cooling power thereof, and which has electrode units arranged and configured such that a high frequency (HF) treatment current generated by an HF generator can be conducted into the tissue, and
• a regulation unit configured and connected to the cooling devices and to the HF generator such that, at the start of the devitalization, a low, first temperature is used to prevent an irreversible change to the tissue directly adjacent to the at least one ablation probe and, at the end of the devitalization, an increased, second temperature is used,
• wherein the regulation unit is configured for setting the first temperature by defining a first treatment current and for setting the second temperature by defining a first treatment voltage and, in each case, a corresponding adjustment of the cooling power.