Transition Metal-Catalyzed C-H Amination Using Unactivated Amines
AssigneeGeorgetown University
InventorTimothy H. Warren
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Abstract
One aspect of the invention relates to a method of animation or amidation, comprising the step of combining a substrate, comprising a reactive C—H bond, and an amine or amide, comprising a reactive N—H bond, in the presence of an oxidizing agent and a metal-containing catalyst, thereby forming a product with a covalent bond between the carbon of the reactive C—H bond and the nitrogen of the reactive N—H bond.
Claims48
A method of amination or amidation, comprising the step of:
- combining a substrate, comprising a reactive C—H bond, and an amine or amide, comprising a reactive N—H bond, in the presence of an oxidizing agent and a metal-containing catalyst, wherein the metal-containing catalyst is a transition metal-containing catalyst, thereby forming a product with a covalent bond between the carbon of the reactive C—H bond and the nitrogen of the reactive N—H bond.
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Dependencies are inferred from the claim text.