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US 2011/0213125 A1Published application
Humanized Antibodies Against Human Interferon-Alpha
AssigneeNovo Nordisk A/S
InventorsLars Anders Svensson, Soren Padkjaer, Birgitte Friedrichsen, Berit Olsen Krogh, Inger Lund Pedersen
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Abstract
The present invention provides humanized anti-human IFN-α monoclonal antibodies useful for therapeutic applications in humans. Preferred antibodies are humanized versions of murine antibodies ACO-1 and ACO-2, as well as variants thereof.
Claims2
1-13. (canceled)
An IgG4 isotype antibody that binds human interferon-α and comprises a VH domain comprising SEQ ID NO:3 and a VL domain comprising SEQ ID NO:6.
Dependencies are inferred from the claim text.