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US 2011/0213006 A1Published application
Compositions and Methods for Treatment of Uncontrolled Cell Growth
AssigneeImmunotrex Corporation
InventorSyed K. Hasan
Life of this patent
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Abstract
Compositions and methods are provided for the treatment of cancer and other diseases of uncontrolled cell growth. Inhibitors of t-RNA and 28s rRNA are provided as are non-functional amino acid residues for charging of t-RNA molecules. Therapeutic application of the above inhibitors is also provided for the treatment of cancer.
Claims20
A method for the treatment of cancer in a patient in need thereof comprising:
- nucleic acid delivery of one or more t-RNA inhibitors to tumor cells in the patient in need thereof wherein the t-RNA inhibitor limits protein production in tumor cells and thereby causes the tumor cells to preferentially die as compared to other non-tumor cells in the patient.
A method for the treatment of cancer in a patient in need thereof comprising:
- nucleic acid delivery of one or more 28s rRNA inhibitors to tumor cells in the patient in need thereof wherein the 28s rRNA inhibitor limits protein production in tumor cells and thereby causes the tumor cells to preferentially die as compared to other non-tumor cells in the patient.
An isolated nucleic acid having a sequence selected from the group consisting of SEQ ID NO:
- 1, SEQ ID NO:
- 2, SEQ ID NO:
- 3, SEQ ID NO:
- 4, SEQ ID NO:
- 5, SEQ ID NO:
- 6, SEQ ID NO:
- 7, and SEQ ID NO:
- 8.
5 more elements
Dependencies are inferred from the claim text.