Novel polymorph of moxifloxacin hydrochloride
AssigneeHetero Research Foundation
InventorsBandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Rapolu Raji Reddy, Dasari Muralidhara Reddy, Musku Madhanmohan Reddy, Deevireddy Bharath Reddy
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Abstract
The present invention relates to novel polymorph of moxifloxacin hydrochloride, processes for its preparation and to pharmaceutical compositions containing it. Thus, for example moxifloxacin hydrochloride is suspended in methanol and water and the pH is adjusted to 1.0-2.0 with concentrated hydrochloric acid at 25° C. and the separated solid is collected and dried to obtain moxifloxacin hydrochloride monohydrate polymorph IV.
Claims10
A polymorph IV of moxifloxacin hydrochloride monohydrate, characterized by an X-ray powder diffractogram having peaks expressed as 2θ angle positions at about 7.5, 9.3, 12.8, 15.1, 16.7, 18.7 and 19.2±0.2 degrees.
Dependencies are inferred from the claim text.