4,4-disubstituted piperidines

Compound of the general formula (I)

• or a pharmaceutically acceptable salt thereof, in which R2 is phenyl, which is substituted by 1-3 radicals, one of which is located in the para-position relative to the bond from the phenyl ring to the remainder of the molecule, selected independently from the group consisting of
• C1-6-alkanoyloxy-C1-6-alkyl,
• C2-6-alkenyl,
• C2-6alkenyloxy,
• C2-6-alkenyloxy-C1-6-alkyl,
• C1-6alkoxy,
• C1-6-alkoxy-C1-6-alkoxy,
• C1-6-alkoxy-C1-6-alkoxy-C1-6-alkoxy,
• C1-6-alkoxy-C1-6-alkoxy-C1-6-alkoxy-C1-6-alkyl,
• C1-6-alkoxy-C1-6-alkoxy-C1-6-alkyl,
• C1-6-alkoxy-C1-6-alkyl,
• C1-6-alkoxy-C1-6-alkylamino-C1-6-alkyl,
• C1-6-alkoxy-C1-6-alkylsulfanyl,
• C1-6-alkoxy-C1-6-alkylsulfanyl-C1-8-alkyl,
• C1-6-alkoxycarbonyl,
• C1-6-alkoxycarbonyloxy-C1-8-alkyl,
• C1-6-alkyl,
• C1-8-alkylsulfanyl,
• C1-6-alkylsulfanyl-C1-6-alkoxy,
• C1-6-alkylsulfanyl-C1-6-alkoxy-C1-6-alkyl,
• C1-6-alkylsulfanyl-C1-6-alkyl,
• C1-6-alkylsulfonyl-C1-6-alkoxy-C1-6-alkyl,
• C1-6-alkylsulfonyl-C1-6-alkyl,
• C2-8-alkynyl,
• optionally N-mono- or N,N-di-C1-6-alkylated amino-C1-6-alkoxy,
• optionally N-mono- or N,N-di-C1-6-alkylated amino-carbonyl-C1-6-alkyl,
• aryl-pyrrolidinyl-C0-8-alkoxy,
• heterocyclyl-pyrrolidinyl-C0-6-alkoxy,
• aryl-C0-6-alkoxy-C1-6-alkoxy,
• aryl-C0-6-alkoxy-C1-6-alkoxy-C1-6-alkyl,
• carboxy-C1-6-alkyl,
• cyano,
• cyano-C1-6-alkyl,
• C3-8-cycloalkyl-C0-6-alkoxy-C1-6-alkoxy,
• C3-8-cycloalkyl-C0-6-alkoxy-C1-6-alkoxy-C1-6-alkyl,
• C3-8-cycloalkyl-C0-6-alkoxy-C1-6-alkyl,
• C3-8-cycloalkyl-C0-6-alkylamino-C1-6-alkyl,
• heterocyclyl-carbonyl-C1-6-alkyl,
• heterocyclyl-sulfanyl-C1-6-alkoxy-C1-6-alkyl and
• heterocyclyl-C2-6-alkoxy-C1-6-alkyl;
• and may, in addition to the aforementioned substituents, also be substituted by a maximum of 2 halogens, the maximum total number of substituents on the phenyl radical of R2 being 3.