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US 2011/0212918 A1Published application
Boron-containing small molecules
AssigneeAnacor Pharmaceuticals, Inc.
InventorsVincent S. Hernandez, Xianfeng Li, Suoming Zhang, Tsutomu Akama, Yanchen Zhang, Yang Liu, Jacob J. Plattner, Michael Richard Kevin Alley, Yasheen Zhou, James A. Nieman
Life of this patent
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Abstract
This invention relates to, among other items, 6-substituted benzoxaborole compounds and their use for treating bacterial infections.
Claims14
A compound, or a salt thereof, having a structure which is
- wherein R5 is H or halogen;
- one of Ra2, Ra3, Ra5 and Ra6 is halogen or —NHC(O)OR30 or alkyl substituted with —C(O)OR30 or alkyl substituted with —S(O)2R30 or alkyl substituted with halogen or alkyl substituted with hydroxy or alkyl substituted with cyano or alkyl substituted with —NHC(O)OR30 or alkyl substituted with unsubstituted oxazolyl or alkyl substituted with alkyl substituted oxazolyl or alkyl substituted with unsubstituted oxadiazolyl or alkyl substituted with alkyl substituted oxadiazolyl or alkyl substituted with —C(O)NHR35,
- wherein R30 is unsubstituted alkyl and R35 is unsubstituted alkyl or unsubstituted cycloalkyl,
- and the remaining members of Ra2, Ra3, Ra5 and Ra6 are H, R10 and R11 are independently selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl.
1 more element
Dependencies are inferred from the claim text.