Pharmaceutical compositions comprising casein derived peptides and methods of use thereof
AssigneesMileutis Ltd., State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization
InventorsJose Mario Iscovich, Nissim Silanikove, Javier Iscovich
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Abstract
The present invention relates to peptides derived from casein and their use in the management of lactating animals, particularly to methods for decreasing the length of the dry period of a lactating livestock animal, for increasing its milk yield and milk hygiene after parturition and for improving the livestock welfare. The present invention further relates to pharmaceutical compositions comprising peptides derived from casein in the form of a sterile solution, which compositions are clear and substantially devoid of micelles.
Claims43
A method for reducing the length of the dry period between cycles of lactation in a lactating animal without negatively affecting the milk yield, comprising administering to the lactating animal a therapeutically effective amount of at least one peptide derived from casein.
A method for increasing the milk yield of a livestock lactating animal after parturition compared to the milk yield of the lactating animal before parturition, comprising administering to the lactating animal a therapeutically effective amount of at least one peptide derived from casein.
A method for increasing milk hygiene of a lactating animal, comprising administering to a mammary gland of the lactating animal a therapeutically effective amount of at least one peptide derived from casein, as to reduce the somatic cell counts (SCC) in the milk as compared to the SCC before peptide administration.
A method for preventing the suffering associated with mammary gland infection or abrupt cessation of milking in a livestock lactating animal, comprising administering to a mammary gland of the lactating animal a therapeutically effective amount of at least one peptide derived from casein, thereby improving the lactating animal welfare.
Dependencies are inferred from the claim text.