Detergent composition
AssigneeNovozymes A/S
InventorsLone Kierstein Nielsen, Lise Munch Mikkelsen, Esben Peter Friis, Juergen Carsten Franz Knoetzel, Ole Simonsen
Life of this patent
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Abstract
Peptide aldehydes containing a ureido group are effective as stabilizers for protease in a detergent composition, and as stabilizers for a second enzyme in a liquid composition with a protease.
Claims14
A liquid detergent composition comprising a surfactant, a protease and a compound of the formula:
- P—O-(Ai-X)n-An+1-H
- wherein one X is the “double N-capping group” CO, CO—CO, CS, CS—CS or CS—CO (most preferably CO), and the other X'es are nothing,
- wherein n=1-10, preferably 2-5, most preferably 3
- wherein i is an integer from 1 to n
- wherein each Ai and An+1 is an amino acid residue having the structure:
- —NH—CR—CO— for a residue to the right of the double N-capping group, or
- —CO—CR—NH— for a residue to the left of the double N-capping group
- wherein R is H— or an optionally substituted alkyl or alkylaryl group which may optionally include a hetero atom and may optionally be linked to the N atom, and
- wherein P is hydrogen or any C-terminal protection group.
A liquid enzyme composition, comprising a protease at a concentration of at least 0.1% by weight of enzyme protein and a compound of the formula:
- P—O-(Ai-X)n-An+1-H
- wherein one X is the “double N-capping group” CO, CO—CO, CS, CS—CS or CS—CO (most preferably CO), and the other X'es are nothing,
- wherein n=1-10, preferably 2-5, most preferably 3
- wherein i is an integer from 1 to n
- wherein each Ai and An+1 is an amino acid residue having the structure:
- —NH—CR—CO— for a residue to the right of the double N-capping group, or
- —CO—CR—NH— for a residue to the left of the double N-capping group
- wherein R is H— or an optionally substituted alkyl or alkylaryl group which may optionally include a hetero atom and may optionally be linked to the N atom, and
- wherein P is hydrogen or any C-terminal protection group.
A liquid enzyme composition, comprising a protease, a second enzyme and a compound of the formula:
- P—O-(Ai-X)n-An+1-H
- wherein one X is the “double N-capping group” CO, CO—CO, CS, CS—CS or CS—CO (most preferably CO), and the other X'es are nothing,
- wherein n=1-10, preferably 2-5, most preferably 3
- wherein i is an integer from 1 to n
- wherein each Ai and An+1 is an amino acid residue having the structure:
- —NH—CR—CO— for a residue to the right of the double N-capping group, or
- —CO—CR—NH— for a residue to the left of the double N-capping group
- wherein R is H— or an optionally substituted alkyl or alkylaryl group which may optionally include a hetero atom and may optionally be linked to the N atom, and
- wherein P is hydrogen or any C-terminal protection group.
A compound having the formula HO-A1-CO-A2-A3-A4-H, wherein A1 is a Phe residue, A2 is an Arg or Gly residue, A3 is a Val or Gly residue, and A4 is a Tyr residue.
Dependencies are inferred from the claim text.