L-amino acid-producing microorganism and a method for producing an l-amino acid
AssigneeAjinomoto Co., Inc.
InventorsRie Takikawa, Yoshihiko Hara, Gen Nonaka, Kazuhiro Takumi
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Abstract
An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae, which has an L-amino acid-producing ability and inherently has a native activity of a glucose dehydrogenase that uses pyrroloquinoline quinone as a coenzyme, but has been modified so that the activity of the glucose dehydrogenase is reduced, in a medium, and collecting the L-amino acid from the medium.
Claims8
A method for producing an L-amino acid comprising:
- A) culturing a bacterium which belongs to the family Enterobacteriaceae and is able to produce an L-amino acid in a medium, and
- B) collecting the L-amino acid from the medium or the bacterium,
- wherein the bacterium has been modified so that the native activity of glucose dehydrogenase, which uses pyrroloquinoline quinone as a coenzyme, is reduced as compared to an unmodified bacterium.
The method according to 1, wherein the bacterium belongs to a genus selected from the group consisting of Pantoea, Enterobacter, Erwinia, Klebsiella, Providencia, Salmonella, Serratia, Morganella, and Yersinia.
Dependencies are inferred from the claim text.