Formulation For Retinoid-Containing Soft Gelatin Capsules
AssigneeGlaxo Group Limited
InventorsGünter Ditzinger, Bernhard Gabriel, Anne-Hortense Schmitt-Hoffmann, Lutz Wevelsiep
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Abstract
A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.
Claims21
Pharmaceutical formulation for retinoids comprising a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides.
A soft oral gelatin capsule comprising a pig gelatin capsule shell filled with a fill mass comprising 9-cis retinoic acid or pharmaceutically acceptable salts or esters thereof as an active ingredient, soybean oil, partially hydrogenated soybean oil, medium chain triglycerides and natural wax.
Dependencies are inferred from the claim text.