Back to results
US 2011/0212168 A1Published application
Composition for targeting dendritic cells
AssigneesLipotek Pty Ltd., Domantis Limited
InventorsJoseph Altin, Ines Atmosukarto, Rudolf Maria De Wildt, Christopher Parish, Jason Price
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to a composition for targeting dendritic cells. In particular, the present disclosure relates to a composition comprising: a) one or more antigens; b) an anti-DC-SIGN immunoglobulin single variable domain; and c) a carrier which carries a) and b). The disclosure further relates to formulations, compositions and devices comprising such anti-DC-SIGN molecules and their use as a medicament and in the treatment of cancer, suitably melanoma.
Claims29
A composition comprising:
- a) one or more antigens;
- b) an anti-DC-SIGN immunoglobulin single variable domain;
- and
- c) a carrier which carries a) and b) the one or more antigens and the anti-DC-SIGN immunoglobulin single variable domain.
1 more element
A method for making a composition comprising:
- i) preparing membrane vesicles;
- ii) preparing a liposomal constituent;
- iii) combining the membrane vesicles and the liposomal constituent with the immunomodulatory factor;
- and iv) adding the anti-DC-SIGN immunoglobulin single variable domain.
1 more element
Dependencies are inferred from the claim text.