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AssigneeUniversity of the Witwatersrand
InventorsYahya E. Choonara, Micheal P. Danckwerts, Viness Pillay
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The invention relates to biodegradable and implantable devices for the in situ delivery of a pharmaceutical composition to a human or animal that comprise a generally discoid body, having at least one aperture through which the body is anchorable by suture, and that are formed from biodegradable polymeric compositions. The invention relates to methods of manufacturing devices for the in situ delivery of a pharmaceutical composition to a human or animal that comprise a generally discoid body, having at least one aperture through which the body is anchorable by suture, and that are formed from biodegradable polymeric compositions. The invention relates to a therapeutic method that comprises inserting a biodegradable and implantable device that comprises a generally discoid body, having at least one aperture through which the body is anchorable by suture, and that is formed from a biodegradable polymeric composition, into a body cavity of a human or animal.
A biodegradable and fully implantable intraocular device for the in situ delivery of a desired pharmaceutical composition to a human or animal eye, said device comprising a pharmaceutical composition within a discoid body having a generally circumferential periphery and being formed from a biodegradable polymeric composition, the body also having a circular aperture in the center of the discoid body whereby said body is anchorable, in use, within the human or animal eye by a suture throughout substantially the entire degradation of the intraocular device, and wherein the circular aperture is dimensioned to provide a substantially constant release profile for the pharmaceutical composition as the body degrades.
A method of manufacturing an intraocular device for the in situ delivery of a desired pharmaceutical composition to a human or animal eye, said method comprising the steps of:
Dependencies are inferred from the claim text.