Nerve Growth Factor Conjugates and Uses Thereof
OwnerMartin Bachmann, Gary Jennings +1inventors
InventorsMartin Bachmann, Gary Jennings, Till Röhn
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Abstract
The present invention is in the fields of medicine, public health, immunology, molecular biology and virology. The invention provides composition comprising a virus-like particle (VLP) linked to at least one antigen, wherein said antigen is NGF antigen. The invention also provides a process for producing the composition. The compositions of this invention are useful in the production of vaccines, in particular, for the treatment of pain. Moreover, the compositions of the invention induce efficient immune responses, in particular antibody responses.
Claims30
A composition comprising:
- (a) a virus-like particle (VLP) with at least one first attachment site;
- and
- (b) at least one antigen with at least one second attachment site,
- wherein said at least one antigen is an NGF protein, an NGF fragment or an NGF mutein;
- and wherein (a) and (b) are linked through said at least one first and said at least one second attachment site.
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Dependencies are inferred from the claim text.